Yintoni i-HDF (i-Hemofiltration)?
UMnu. Wang oneminyaka engama-62 ubudala, obene-hemodialysis iminyaka emi-5, wayenengxaki yokurhawuzelelwa okunzulu (okubi kakhulu ebusuku) kunye nentlungu engapheliyo edolweni kangangeenyanga ezi-6. Iimpawu zakhe azizange ziphucuke kangako nge-dialysis eqhelekileyo, kwaye uphononongo olulandelayo lwabonisa i-PTH ephezulu. Ekuqaleni wayethandabuza ngenkqubo enzima ye-HDF ecetyiswa ngoogqirha, wavuma ukuyizama. Emva kweeseshoni ezininzi, ukurhawuzelelwa kwakhe kwaphela, walala kakuhle, isiyezi esinxulumene ne-dialysis kunye nokuqaqamba kwemisipha kwehla kakhulu, kwaye imeko yakhe yengqondo yaphucuka. Ngoku uthatha inyathelo lokucebisa unyango kwabanye abaguli be-dialysis: "Olu hlobo luphuculweyo lwe-dialysis lwenza umahluko ngokwenene!"
01 Yintoni i-HDF(IsiNgesi)Ukuhluzwa kwegazi？？
Ngamafutshane,I-HDF yindibaniselwano ye-hemodialysis (HD) kunye ne-hemofiltration. Igcina umsebenzi oyintloko we-HD ekucoceni iimolekyuli ezincinci (umz. i-urea, i-creatinine), ngelixa yongeza inkqubo yokucoca. Njengezintso eziphilileyo, isebenzisa i-gradient yoxinzelelo ukususa iityhefu eziphakathi nezinkulu (umz. i-β2-microglobulin, i-parathyroid hormone).
02 Iingenelo eziphambili ze-HDF xa kuthelekiswayesintui-dialysis
Kwizigulane ezixiliswayo ixesha elide, ukuqokelelwa kwetyhefu yemolekyuli ephakathi nenkulu yeyona nto ibangela ukurhawuzelelwa kwesikhumba, iintlungu zamathambo kunye neengxaki zentliziyo. Inzuzo ephambili ye-HDF ijoliswe ngqo kule ngxaki:
(1) Ukususwa ngokupheleleyo kwetyhefu
Isusa iityhefu ezincinci zemolekyuli (urea creatinine) kunye neemolekyuli eziphakathi/ezikhulu ezinzima ukuzisusa (β2-microglobulin, PTH) ezinciphisa iingxaki ezifana ne-renal osteopathy kunye nokurhawuzelelwa lusu.
（2） Amava Onyango Akhululekileyo Ngakumbi
Ukongezwa kolwelo endaweni yalo kuzinzisa ibhalansi ye-electrolyte kunye nolwelo, kunciphisa umngcipheko woxinzelelo lwegazi, isiyezi, ukuqaqamba kwemisipha, kunye nokudinwa emva kwe-dialysis.
（3） Iingenelo ezibalulekileyo zexesha elide
I-HDF eqhelekileyo iphucula isondlo, umgangatho wokulala kunye nempilo yentliziyo, iphucula umgangatho wobomi bezigulane ze-dialysis ixesha elide.
03 Ngabaphi abaguli bezintso abafanelekileyo ukukhetha i-HDF?
- Izigulana eziye zafumana iingxaki ezicacileyo ezinxulumene ne-dialysis, ezifana nokurhawuzelela ulusu okuphindaphindiweyo, iintlungu zamathambo, okanye ukungonwabi kwamalungu.
- Izigulane ezinezinga eliphezulu le-parathyroid hormone (PTH) ezihlala zinzima ukuzilawula nge-hemodialysis eqhelekileyo.
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Izigulana ezihlala ziziva zingakhululekanga ngexesha lokucoca i-dialysis, ezifana noxinzelelo lwegazi oluphantsi okanye ukuqaqamba kwemisipha.
- Izigulana ezinethemba lokuphucula unyango ngakumbi kwaye zinciphise umngcipheko weengxaki ezihlala ixesha elide.
Ukufaneleka konyango lwe-HDF kufuneka kuhlolwe ngokupheleleyo ngugqirha oqeqeshiweyo ngokusekelwe kwimeko ethile yesigulana kunye neziphumo zovavanyo lwelebhu. Akucetyiswa ukuba wenze isigqibo ngokwakho.
04 Yintoni Ekufuneka Izigulana Ziyiqaphele Xa Ziphantsi kwe-HDF?
(1). Akukho mfuneko yokulungiselela okongezelelweyoInkqubo yonyango kunye nendlela yokubhoboza ye-HDF ngokusisiseko ziyafana nezo ze-hemodialysis eqhelekileyo. Izigulana azidingi kufunda utyando olongezelelweyo, kwaye akufuneki zitshintshe i-dialysis frequency (ngesiqhelo zihlala kathathu ngeveki).
(2). Nika ingqalelo kwi-Anticoagulation kunye ne-Replacement Fluid
Ii-anticoagulants (umz., i-heparin enobunzima obuphantsi kweemolekyuli) zisetyenziswa ngexesha lonyango ukuthintela ukujiya kwegazi. Izigulana ezinesifo sokopha kufuneka zazise oogqirha bazo kwangaphambili.Ulwelo oluza kutshintshwa alunamagciwane kwaye lulungiswe ngokulinganayo sisibhedlele, ngoko ke ukhuseleko lwalo luqinisekisiwe ngokupheleleyo.
Ixesha leposi: Jan-15-2026
