Ngaba iDialyzer ingaphinda isetyenziswe kunyango lweHemodialysis?

I-Dialyzer, esetyenziswa kakhulu kunyango lwe-dialysis yezintso, isebenzisa umgaqo we-membrane engena kumanzi ukuze ingenise igazi elivela kwizigulane ezingasebenzi kakuhle kwezintso kwaye i-dialysate ingene kwi-dialyzer ngaxeshanye, kwaye yenze ukuba la macala omabini ajikeleze kwicala elichaseneyo kumacala omabini e-membrane ye-dialysis, ngoncedo lwe-solute gradient emacala omabini, i-osmotic gradient, kunye ne-hydraulic pressure gradient. Le nkqubo yokusasazwa inokususa iityhefu kunye namanzi amaninzi emzimbeni ngelixa iphinda izalise izinto ezifunekayo emzimbeni kwaye igcine ibhalansi ye-electrolytes kunye ne-acid-base.

Ii-dialyzers zenziwe ikakhulu zizakhiwo zenkxaso kunye nee-membrane ze-dialysis. Iintlobo ze-hollow fibers zisetyenziswa kakhulu kwizonyango. Ezinye ii-hemodialyzers zenzelwe ukuba zisetyenziswe kwakhona, zinesakhiwo esikhethekileyo kunye nezixhobo ezinokumelana nokucocwa okuninzi kunye nokubulala iintsholongwane. Okwangoku, ii-dialyzers ezilahlwayo kufuneka zilahlwe emva kokusetyenziswa kwaye azinakusetyenziswa kwakhona. Nangona kunjalo, kubekho impikiswano kunye nokudideka malunga nokuba ii-dialyzers kufuneka zisetyenziswe kwakhona na. Siza kuhlola lo mbuzo kwaye sinike ingcaciso ngezantsi.

Iingenelo kunye nokungalungi kokusebenzisa kwakhona ii-dialyzers

(1) Ukuphelisa isifo sokusetyenziswa kokuqala.
Nangona zininzi izinto ezibangela isifo sokusetyenziswa kokuqala, njengesibulali-ntsholongwane se-ethylene oxide, izinto ezikwi-membrane, ii-cytokines eziveliswa kukudibana kwegazi kwe-dialysis membrane, njl.njl., nokuba zeziphi izizathu, amathuba okuba kwenzeke aya kuncipha ngenxa yokusetyenziswa ngokuphindaphindiweyo kwe-dialyzer.

(2) Phucula ukuhambelana kwe-bio-compatibility ye-dialyzer kwaye unciphise ukusebenza kwenkqubo yomzimba yokuzikhusela.
Emva kokusebenzisa i-dialyzer, umaleko wefilimu yeproteni uncamathiselwa kumphezulu wangaphakathi we-membrane, nto leyo enokunciphisa impendulo yefilimu yegazi ebangelwa yi-dialysis elandelayo, kwaye inciphise ukusebenza kwe-complement, i-neutrophil degranulation, ukusebenza kwe-lymphocyte, ukuveliswa kwe-microglobulin, kunye nokukhululwa kwe-cytokine.

(3) Impembelelo yesantya sokususwa kwenkunkuma.
Izinga lokususwa kwe-creatinine kunye ne-urea alinciphi. Ii-dialyzers zokusetyenziswa kwakhona ezifakwe i-formalin kunye ne-sodium hypochlorite eyongeziweyo zinokuqinisekisa ukuba amazinga okususwa kwezinto eziphakathi nezinkulu ze-molecular (iVital12 kunye ne-inulin) azitshintshi.

(4) Nciphisa iindleko ze-hemodialysis.
Akukho mathandabuzo ukuba ukusetyenziswa kwakhona kwe-dialyzer kunokunciphisa iindleko zonyango lwempilo kubantu abangasebenzi kakuhle kwezintso kwaye kubonelele ngokufikelela kwii-hemodialyzer ezingcono kodwa ezibiza kakhulu.
Kwangaxeshanye, iingxaki zokusetyenziswa kwakhona kwe-dialyzer nazo ziyabonakala.

(1) Iimpendulo ezingalunganga kwizibulali-ntsholongwane
Ukubulala iintsholongwane nge-Peracetic acid kuya kubangela ukubola kunye nokubola kwe-dialysis membrane, kwaye kususe neeproteni ezigcinwe kwi-membrane ngenxa yokusetyenziswa okuphindaphindiweyo, okwandisa amathuba okusebenza kwe-complement. Ukubulala iintsholongwane nge-formalin kunokubangela i-Anti-N-antibody kunye ne-allergies kulusu kwizigulana.

(2) Yandisa amathuba okungcoliswa yibhaktiriya kunye ne-endotoxin ye-dialyzer kwaye yandise umngcipheko wosulelo oluhambelanayo

(3) Ukusebenza kwe-dialyzer kuyachaphazeleka.
Emva kokuba i-dialyzer isetyenzisiwe izihlandlo ezininzi, ngenxa yeeproteni kunye namahlwili egazi avimba ii-fiber bundles, indawo esebenzayo iyancitshiswa, kwaye izinga lokucoca kunye nezinga lokuhluza liya kuncipha kancinci kancinci. Indlela eqhelekileyo yokulinganisa umthamo we-fiber bundle ye-dialyzer kukubala umthamo opheleleyo wazo zonke ii-fiber bundle lumens kwi-dialyzer. Ukuba umlinganiselo womthamo opheleleyo kwi-dialyzer entsha ungaphantsi kwe-80%, i-dialyzer ayinakusetyenziswa.

(4) Yandisa amathuba okuba izigulane kunye nabasebenzi bezonyango bachaphazeleke ziikhemikhali.
Ngokusekelwe kuhlalutyo olungentla, ukucoca kunye nokubulala iintsholongwane kunokulungisa iintsilelo zokusetyenziswa kwakhona kwee-dialyzers ukuya kuthi ga kwinqanaba elithile. I-dialyzer inokusetyenziswa kwakhona kuphela emva kweenkqubo zokucoca ezingqongqo kunye nokubulala iintsholongwane kunye novavanyo oluphumeleleyo ukuqinisekisa ukuba akukho kuqhekeka okanye ukuvaleka kwe-membrane ngaphakathi. Ngokungafaniyo nokulungiswa kwendabuko ngesandla, ukusetyenziswa koomatshini bokulungisa ii-dialyzer ngokuzenzekelayo kungenisa iinkqubo ezimiselweyo kwi-dialyzer reprocessing ukunciphisa iimpazamo kwimisebenzi yesandla. Umatshini unokuhlanjwa ngokuzenzekelayo, ukubulala iintsholongwane, ukuvavanya, kunye nokukhupha, ngokweenkqubo kunye nemilinganiselo yokuseta, ukuphucula isiphumo sonyango lwe-dialysis, ngelixa kuqinisekiswa ukhuseleko kunye nococeko lwesigulana.