Ngaba iDialyzer ingaphinda isetyenziswe kuNyango lweHemodialysis?

I-Dialyzer, into ebalulekileyo enokutyiwa kunyango lwe-dialysis yezintso, isebenzisa umgaqo we-membrane ekwazi ukungena ngaphakathi ukwazisa igazi elisuka kwizigulana ezingaphumeleliyo kwizintso kunye ne-dialysate kwi-dialyzer ngaxeshanye, kwaye zenze ukuba zombini zihambe zisiya kumacala omabini kumacala omabini. I-membrane ye-dialysis, ngoncedo lwamacala amabini e-solute gradient, i-osmotic gradient, kunye ne-hydraulic pressure gradient. Le nkqubo yokusabalalisa inokususa i-toxins kunye namanzi amaninzi emzimbeni ngelixa izalisa izinto ezifunekayo zomzimba kunye nokugcina ibhalansi ye-electrolytes kunye ne-asidi-base.

I-dialyzers iqulunqwe kakhulu yinkxaso yenkxaso kunye ne-dialysis membranes. Iintlobo zefiber ezingenanto zisetyenziswa kakhulu kunyango lwezonyango. Ezinye iihemodialyzers ziyilelwe ukuba ziphinde zisetyenziswe, kunye nolwakhiwo olukhethekileyo kunye nezixhobo ezinokumelana nokucocwa okuninzi kunye nokuvalwa. Okwangoku, ii-dialyzers ezilahlayo kufuneka zilahlwe emva kokusetyenziswa kwaye azinakuphinda zisetyenziswe. Nangona kunjalo, kuye kwakho impikiswano kunye nokudideka malunga nokuba i-dialyzers kufuneka iphinde isetyenziswe. Siza kuwuphonononga lo mbuzo kwaye sinikeze ingcaciso ngezantsi.

Izinto eziluncedo kunye nezingeloncedo zokuphinda zisebenzise iidialyzer

(1) Ukuphelisa i-syndrome yokusetyenziswa kokuqala.
Nangona izinto ezininzi zibangela i-syndrome yokuqala yokusetyenziswa, njenge-disinfectant ye-ethylene oxide, i-membrane imathiriyeli, i-cytokines eveliswa luqhagamshelwano lwegazi lwe-dialysis membrane, njl. kusetyenziso oluphindaphindiweyo lwe-dialyzer.

(2) Phucula i-bio-compatibility ye-dialyzer kunye nokunciphisa ukusebenza kwe-immune system.
Emva kokusebenzisa i-dialyzer, umaleko wefilimu yeprotein uncanyathiselwe kumphezulu wangaphakathi we-membrane, enokunciphisa ukusabela kwefilimu yegazi okubangelwa yi-dialysis elandelayo, kunye nokunciphisa ukuvuselela okuhambelanayo, i-neutrophil degranulation, activation lymphocyte, ukuveliswa kwe-microglobulin, kunye nokukhululwa kwe-cytokine. .

(3) Impembelelo yomlinganiselo wokukhutshwa.
Izinga lokucocwa kwe-creatinine kunye ne-urea ayinciphisi. I-dialyzers ephinda isetyenziswe i-disinfected nge-formalin kunye ne-sodium hypochlorite eyongeziweyo inokuqinisekisa ukuba amazinga okukhutshwa kwezinto eziphakathi kunye ezinkulu ze-molecular (Vital12 kunye ne-inulin) zihlala zingatshintshi.

(4) Ukunciphisa iindleko ze-hemodialysis.
Akukho mathandabuzo okuba ukusetyenziswa kwakhona kwe-dialyzer kunokunciphisa iindleko zokhathalelo lwempilo kwizigulana ezingaphumeleliyo kwizintso kwaye kunikeze ukufikelela kwiihemodialyzers ezingcono kodwa ezibiza kakhulu.
Kwangaxeshanye, ukusilela kokusetyenziswa kwakhona kwe-dialyzer kuyabonakala.

(1) Iimpendulo ezingalunganga kwizibulali ntsholongwane
I-Peracetic acid disinfection iya kubangela i-denaturation kunye nokubola kwe-membrane ye-dialysis, kwaye iphinde isuse iiprotheni ezigcinwe kwi-membrane ngenxa yokusetyenziswa ngokuphindaphindiweyo, ukwandisa amathuba okusebenza okuhambelanayo. Ukubulala iintsholongwane kwe-Formalin kunokubangela i-Anti-N-antibody kunye ne-skin allergies kwizigulana

(2) Yongeza ithuba lokungcoliseka kwebhaktiriya kunye ne-endotoxin ye-dialyzer kwaye yonyuse umngcipheko wosulelo olunqamlezayo.

(3) Ukusebenza kwe-dialyzer kuphenjelelwa.
Emva kokuba i-dialyzer isetyenziswe ngamaxesha amaninzi, ngenxa yeprotheyini kunye negazi elithintela i-fiber bundles, indawo esebenzayo iyancitshiswa, kwaye izinga lokucoca kunye nesantya se-ultrafiltration siya kuncipha ngokuthe ngcembe. Indlela eqhelekileyo yokulinganisa umthamo we-fiber bundle ye-dialyzer kukubala umthamo opheleleyo wazo zonke i-lumens ze-fiber bundle kwi-dialyzer. Ukuba umlinganiselo womthamo opheleleyo kwi-dialyzer entsha ye-brand ingaphantsi kwe-80%, i-dialyzer ayikwazi ukusetyenziswa.

(4)Ukwandisa amathuba okuba izigulane kunye nabasebenzi bezonyango babe sesichengeni kwii-reagents zemichiza.
Ngokusekwe kolu hlalutyo lungentla, ukucocwa kunye nokubulala iintsholongwane kunokwenza iintsilelo zokuphinda usebenzise i-dialyzers ukuya kwinqanaba elithile. I-dialyzer ingaphinda isetyenziswe kuphela emva kokucoca ngokungqongqo kunye neenkqubo zokubulala iintsholongwane kunye neemvavanyo ezigqithisiweyo zokuqinisekisa ukuba akukho ukugqabhuka kwe-membrane okanye ukuvaleka ngaphakathi. Ngokwahlukileyo kwi-reprocessing yemveli yesandla, ukusetyenziswa komatshini wokucofa i-dialyzer ngokuzenzekelayo kwazisa iinkqubo ezisemgangathweni kwi-dialyzer reprocessing ukunciphisa iimpazamo ekusebenzeni ngesandla. Umatshini unokuhlanjululwa ngokuzenzekelayo, u-disinfect, uvavanye, kwaye uphazamise, ngokwemigaqo yokumisela kunye neeparitha, ukuphucula umphumo wonyango lwe-dialysis, ngelixa uqinisekisa ukhuseleko lwesigulane kunye nococeko.